SP7 Antibody / OSX / Osterix

Transcription factor Sp7, also called Osterix (Osx), is a protein that in humans is encoded by the SP7 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q8TDD2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A human recombinant partial protein (amino acids A2-E241) was used as the immunogen for the SP7 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the SP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SP7 antibody is available for research use only.

Storage Conditions

After reconstitution, the SP7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SP7 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HeLa, 2) U-87 MG, 3) MDA-MB-453, 4) MCF7, 5) Jurkat, 6) ThP-1 and rat 7) lung, 8) thymus, 9) skeletal muscle, 10) testis and mouse 11) lung and 12) thymus lysate with SP7 antibody. Predicted molecular weight ~45 kDa.