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RAG1 Antibody / Recombination activating gene 1

Recombination activating gene 1 also known as RAG-1 is a protein that in humans is encoded by the RAG1 gene. The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL

UniProt

P15918

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Amino acids KHHWLYTSKYLQKFMNA from the human protein were used as the immunogen for the RAG1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the RAG1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This RAG1 antibody is available for research use only.

Storage Conditions

After reconstitution, the RAG1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the RAG1 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) human Jurkat and 2) mouse thymus lysate with RAG1 antibody. Predicted molecular weight ~120 kDa.

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