EIF4E Recombinant Antibody
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Product Specifications
UniProt
P06730
Host
Rabbit
Immunogen
A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.
Clonality
Monoclonal
Isotype
IgG
Type
Recombinant
Applications
WB
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the EIF4E antibody at -20oC.
Limitations
This EIF4E antibody is available for research use only.
CAS Number
9000-83-3
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