14-3-3 zeta/delta Antibody / YWHAZ
14-3-3 protein zeta/delta is a protein that in humans is encoded by the YWHAZ gene on chromosome 8. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Product Specifications
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL
UniProt
P63104
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids LLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQ were used as the immunogen for the 14-3-3 zeta antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This 14-3-3 zeta antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/14-3-3-zetadelta-antibody-ywhaz-rq4280
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the 14-3-3 zeta antibody should be determined by the researcher.
CAS Number
9007-83-4
Location
Cytoplasm, nucleus
Image Legend
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