CIAP1 Antibody / BIRC2

Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, Flow: 1-3ug/million cells, Immunofluorescence/Immunocytochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q13490

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant human protein corresponding to amino acids D320-T570 was used as the immunogen for the cIAP1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, IF/ICC, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the cIAP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This cIAP1 antibody is available for research use only.

Storage Conditions

After reconstitution, the cIAP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the cIAP1 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) HeLa, 2) Jurkat, 3) MCF7, 4) COLO320, 5) U-87 MG, 6) A549, 7) rat thymus, 8) mouse thymus and 9) mouse testis lysate with cIAP1 antibody at 0.5ug/ml. Predicted molecular weight ~70 kDa.