EGR2 Antibody

Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. This gene is mapped to 10q21.3. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D(CMT1D), Charcot-Marie-Tooth disease type 4E(CMT4E), and with Dejerine-Sottas syndrome(DSS). EGR2 assists with SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Product Specifications

UniProt

P11161

Host

Rabbit

Immunogen

An amino acid sequence from the N-terminus of human Early growth response protein 2 (TMSQTQPDLDHLYSPP) was used as the immunogen for this EGR2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the EGR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.