N-Cadherin Antibody

NCAD is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). Human and mouse nucleotide sequences are 96% identical. The mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. The human Ncad gene contains 16 exons and its sequence is highly similar to both the mouse gene (including the large first and second introns) and other cadherin genes. Cadherins regulates dendritic spine morphogenesis.