SSH3BP1 Antibody
ABI1 is a human homolog of mouse Abl-interactor-1(Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor(GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.
Product Specifications
UniProt
Q8IZP0
Host
Rabbit
Immunogen
An amino acid sequence from the C-terminus of human SSH3BP1 (WYEGVCNRVTGL) was used as the immunogen for this SSH3BP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This SSH3BP1 antibody is available for research use only.
CAS Number
9007-83-4
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