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JIP1 Antibody / MAPK8IP1

JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

Product Specifications

UniProt

Q9UQF2

Host

Rabbit

Immunogen

A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IF, FACS, IHC-P, WB

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MAPK8IP1 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6685268/datasheet/f55015-0.4ml.pdf

CAS Number

9007-83-4

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