G6PC Antibody

Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

P35575

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 123-149 from the human protein was used as the immunogen for the G6PC antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the G6PC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This G6PC antibody is available for research use only.

Storage Conditions

Aliquot the G6PC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the G6PC antibody may be required due to differences in protocols and secondary/substrate sensitivity.