ACVR1 Antibody / ALK2
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.
Product Specifications
UniProt
P37172
Host
Rabbit
Immunogen
A portion of amino acids 137-166 from the mouse protein was used as the immunogen for the ALK2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ALK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ALK2 antibody is available for research use only.
CAS Number
9007-83-4
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