AIFM1 Antibody / AIF / Apoptosis-Inducing Factor
AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
Product Specifications
UniProt
O95831
Host
Rabbit
Immunogen
A portion of amino acids 70-98 from the human protein was used as the immunogen for the AIF antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC-P, WB, IF
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AIF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AIF antibody is available for research use only.
CAS Number
9007-83-4
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