PSMB1 Antibody
PSMB1 is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Product Specifications
UniProt
P20618
Host
Rabbit
Immunogen
A portion of amino acids 214-241 from the human protein was used as the immunogen for the PSMB1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IF, IHC-P, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PSMB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PSMB1 antibody is available for research use only.
CAS Number
9007-83-4
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