SMPD1 Antibody / Acid Sphingomyelinase
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Product Specifications
UniProt
P17405
Host
Rabbit
Immunogen
A portion of amino acids 391-419 from the human protein was used as the immunogen for the Acid Sphingomyelinase antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, WB, FACS
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Acid Sphingomyelinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Acid Sphingomyelinase antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6683987/datasheet/f54362-0.08ml.pdf
CAS Number
9007-83-4
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