RHBDF2 Antibody

Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

Q6PJF5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 80-109 from the human protein was used as the immunogen for the RHBDF2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the RHBDF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This RHBDF2 antibody is available for research use only.

Storage Conditions

Aliquot the RHBDF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the RHBDF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, plasma membrane

Image Legend

Western blot testing of human 1) RPMI-8226, 2) A549, 3) A431, 4) HT-1080 and 5) MCF7 cell lysate with RHBDF2 antibody. Predicted molecular weight ~97 kDa.