INTS3 Antibody

Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

Q68E01

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Amino acids 518-551 from the human protein were used as the immunogen for this INTS3 antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Antibody in 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the INTS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This INTS3 antibody is available for research use only.

Storage Conditions

Aliquot the INTS3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the INTS3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of INTS3 antibody at 1:2000 + Lane 1: human 293, 2: human HeLa, 3: human Jurkat lysate and 4: mouse NIH3T3 lysate. Predicted molecular weight ~118 kDa.