TPX2 Antibody / Targeting protein for Xklp2
Targeting protein for Xklp2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Product Specifications
UniProt
Q9ULW0
Host
Mouse
Immunogen
A partial recombinant protein corresponding to amino acids 1-531 from the human protein was used as the immunogen for the TPX2 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TPX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TPX2 antibody is available for research use only.
CAS Number
9007-83-4
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