TIGIT Antibody
TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Product Specifications
UniProt
Q495A1
Host
Rabbit
Immunogen
A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TIGIT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TIGIT antibody is available for research use only.
CAS Number
9007-83-4
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