Hopx Antibody
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.
Product Specifications
UniProt
Q8R1H0
Host
Rabbit
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Hopx antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Hopx antibody is available for research use only.
CAS Number
9007-83-4
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