von Willebrand Factor Antibody (vWF)
Important in the maintenance of hemostasis, von Willebrand Factor promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [UniProt]
Product Specifications
UniProt
P04275
Host
Mouse
Immunogen
This vWF antibody was produced from a mouse immunized with human recombinant protein.
Clonality
Monoclonal
Isotype
IgG1
Applications
WB, IHC, FACS, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the vWF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This vWF antibody is available for research use only.
CAS Number
9007-83-4
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