PCNA Antibody
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Product Specifications
UniProt
P12004
Host
Mouse
Immunogen
A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.
Clonality
Monoclonal
Isotype
IgG1
Applications
IHC, WB, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the PCNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PCNA antibody is available for research use only.
CAS Number
9007-83-4
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