RBPMS Antibody
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
Product Specifications
UniProt
Q93062
Host
Rabbit
Immunogen
A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RBPMS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RBPMS antibody is available for research use only.
CAS Number
9007-83-4
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