CDC20 Antibody
CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome) . It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
Q12834
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 57-84 from the human protein was used as the immunogen for this CDC20 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CDC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CDC20 antibody is available for research use only.
Storage Conditions
Aliquot the CDC20 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CDC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Pig
Image Legend
Western blot analysis of CDC20 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the CDC20 gene.
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