IGF1 Receptor Antibody (IGF1R)
The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Product Specifications
UniProt
P08069
Host
Rabbit
Immunogen
A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IGF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IGF1R antibody is available for research use only.
CAS Number
9007-83-4
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