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Phospho-Dnmt1 Antibody (pS1105)

DNA (cytosine-5-) -methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Dot blot: 1:500

UniProt

P26358

Host

Rabbit

Reactivity

Human

Immunogen

This phospho-Dnmt1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1105 of human Dnmt1.

Clonality

Polyclonal

Isotype

Ig

Applications

DB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the phospho-Dnmt1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This phospho-Dnmt1 antibody is available for research use only.

Storage Conditions

Aliquot the phospho-Dnmt1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the phospho-Dnmt1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat

Image Legend

Dot blot analysis of phospho-Dnmt1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

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