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SMAD4 Antibody (phospho-T277)

Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Product Specifications

UniProt

Q13485

Host

Rabbit

Immunogen

This phospho-SMAD4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT277 of human SMAD4.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, IF, DB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the phospho-SMAD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This phospho-SMAD4 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6680945/datasheet/f48451-0.08ml.pdf

CAS Number

9007-83-4

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