Integrin beta 2 Antibody
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1) . Two transcript variants encoding the same protein have been identified for this gene.
Product Specifications
Specifications
Western blot: 1:1000
UniProt
P05107
Host
Rabbit
Reactivity
Human
Immunogen
This Integrin beta 2 antibody was produced from rabbits immunized with a recombinant ITGB2/CD18 protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Integrin beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Integrin beta 2 antibody is available for research use only.
Storage Conditions
Aliquot the Integrin beta 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/integrin-beta-2-antibody-f46195
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Integrin beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
CAS Number
9007-83-4
Image Legend
Integrin beta 2 antibody western blot analysis in 293 lysate. Predicted/Observed molecular weight: 85~95KD depending on glycosylation level.
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