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HMGB1 Antibody

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). [UniProt]

Product Specifications

UniProt

P09429

Host

Rabbit

Immunogen

A portion of amino acids 152-180 from the human protein was used as the immunogen for this HMGB-1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the HMGB-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HMGB-1 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6680267/datasheet/f45590-0.08ml.pdf

CAS Number

9007-83-4

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