GPNMB Antibody
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
UniProt
Q14956
Host
Rabbit
Immunogen
A portion of amino acids 541-569 from the human protein was used as the immunogen for this GPNMB antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the GPNMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GPNMB antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6680248/datasheet/f45454-0.4ml.pdf
CAS Number
9007-83-4
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