GPNMB Antibody
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q14956
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 541-569 from the human protein was used as the immunogen for this GPNMB antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the GPNMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GPNMB antibody is available for research use only.
Storage Conditions
Aliquot the GPNMB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the GPNMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
GPNMB antibody western blot analysis in CEM lysate.
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