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A2M Antibody / Alpha-2-macroglobulin

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P01023

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1162-1192 from the human protein was used as the immunogen for this A2M antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the A2M antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This A2M antibody is available for research use only.

Storage Conditions

Aliquot the A2M antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.nsjbio.com/tds-pdf/a2m-antibody-alpha-2-macroglobulin-f44166

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the A2M antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

A2M antibody western blot analysis in human placenta tissue lysate. Predicted molecular weight: ~163/200kDa (unmodified/glycosylated) .

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