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NLRP12 Antibody

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Product Specifications

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

P59046

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NLRP12 antibody is available for research use only.

Storage Conditions

Aliquot the NLRP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.nsjbio.com/tds-pdf/nlrp12-antibody-f43436

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

CAS Number

9007-83-4

Image Legend

NLRP12 antibody western blot analysis in human placenta tissue lysate. Predicted molecular weight: ~119kDa, routinely observed at 100~119kDa.

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