CD43 Antibody
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:250
UniProt
P16150
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 230-257 from the human protein was used as the immunogen for this CD43 antibody.
Clonality
Monoclonal
Isotype
IgM
Clone
423CT7.9.2
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD43 antibody is available for research use only.
Storage Conditions
Aliquot the CD43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CD43 antibody western blot analysis in SK-BR-3 lysate. Predicted molecular weight 45-115 kDa depending on glycosylation level.
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