L-6355
Product Specifications
UNSPSC Description
L-6355 is an Amiodarone (HY-14187) related compound, which inhibits Ca2+/calmodulin activated cyclic nucleotide phosphodiesterase with an IC50 value of 0.65 μM. L-6355 is promising for research of antiarrhythmic and antianginal agent[1].
Target Antigen
Calmodulin; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-6355.html
Smiles
O=C(C1=C(CCCC)OC2=C1C=CC=C2)C3=CC=C(C(I)=C3)OCCN(CC)CC
Molecular Weight
519.42
References & Citations
[1]Nokin P, et al. Amiodarone is a potent calmodulin antagonist. Naunyn Schmiedebergs Arch Pharmacol. 1989 Apr;339(4):367-73.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124176/L-6355-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124176/
Clinical Information
No Development Reported
CAS Number
85642-08-6
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