(R)-SKF 38393 (hydrochloride)
Product Specifications
Product Name Alternative
(±)-SKF-38393 (hydrochloride); SKF-38393A (hydrochloride)
UNSPSC Description
(R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel[1].
Target Antigen
Dopamine Receptor; Potassium Channel
Type
Reference compound
Related Pathways
GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-skf-38393-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=C2[C@H](CNCCC2=C1)C3=CC=CC=C3)O.Cl
Molecular Weight
291.77
References & Citations
[1]Kuzhikandathil EV, et, al. Classic D1 dopamine receptor antagonist R-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (SCH23390) directly inhibits G protein-coupled inwardly rectifying potassium channels. Mol Pharmacol. 2002 Jul;62(1):119-26.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12520B/R-SKF-38393-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12520B/
Clinical Information
No Development Reported
CAS Number
81702-42-3
Available Sizes
Curated Selection
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