Aztreonam

Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3) .

Product Specifications

CAS Number

[78110-38-0]

Product Name Alternative

SQ-26,776

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Penicillin-binding protein (PBP)

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Aztreonam.html

Concentration

10mM

Purity

99.64

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

Smiles

CC(C)(O/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@H](C)N(S(=O)(O)=O)C2=O)=O)C(O)=O

Molecular Formula

C13H17N5O8S2

Molecular Weight

435.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Kobayashi Y, et al. Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. J Antimicrob Chemother. 1992 Dec;30 (6) :871-2.|[2]Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4 (5) :516-26.