SP-alkyne
SP-alkyne (compound 8) suppresses IL-2 production and AP-1 and NFAT reporters[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sp-alkyne.html
Solubility
10 mM in DMSO
Smiles
C#CC1=CC(NC(C2=C(C(F)(F)F)N=C(Cl)N=C2)=O)=CC(C(F)(F)F)=C1
Molecular Formula
C15H6ClF6N3O
Molecular Weight
393.67
References & Citations
[1]Yi Fan Chen, et al. Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation. Nat Chem Biol. 2024 Mar 25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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