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Retifanlimab

Retifanlimab is an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb) . Retifanlimab can be used for the research of gastroesophageal adenocarcinoma (GEA) [1].

Product Specifications

CAS Number

[2079108-44-2]

Product Name Alternative

INCMGA-00012; MGA-012

UNSPSC

12352203

Target

PD-1/PD-L1

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/retifanlimab.html

Purity

96.84

Solubility

10 mM in DMSO

Smiles

[Retifanlimab]

Molecular Weight

(145.35 kDa)

References & Citations

[1]D V T Catenacci, et al. Margetuximab with retifanlimab as first-line therapy in HER2+/PD-L1+ unresectable or metastatic gastroesophageal adenocarcinoma: MAHOGANY cohort A. ESMO Open. 2022 Oct;7 (5) :100563.|[2]Shaukat A, et al. Retifanlimab: a breakthrough for the management of Merkel cell carcinoma[J]. IJS Oncology, 2023, 8 (3) : 18-20.|[3]La Motte-Mohs R, et al. Preclinical characterization of MGD013, a PD-1 x LAG-3 bispecific DART® molecule[J]. Lung, 2017, 28 (10/18) : 56.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Available Sizes

Curated Selection

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