(+/-) 13-HODE cholesteryl ester
(±) 13-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester.
Product Specifications
CAS Number
[167354-91-8]
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/13-hode-cholesteryl-ester.html
Smiles
CCCCCC(O)/C=C/C=C\CCCCCCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@@]4(C)[C@](CC[C@]4([H])[C@@H](CCCC(C)C)C)([H])[C@]3([H])CC=C2C1)=O
Molecular Formula
C45H76O3
Molecular Weight
665.08
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Belkner, et al. The oxygenation of cholesterol esters by the reticulocyte lipoxygenase. FEBS Lett. 279 (1), 110-114 (1991) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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