Orexin-B (Human)

<strong>Orexin-B (Human)</strong> <strong>Catalog number:</strong> MDP0719 <strong>CAS Number: </strong>136661-76-2 <strong>Sequence: </strong>Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 2899.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Mahoney CE, Cogswell A, Koralnik IJ, Scammell TE. The neurobiological basis of narcolepsy Nat Rev Neurosci. 2019 Feb;20(2):83-93. 2: Toor B, Ray LB, Pozzobon A, Fogel SM. Sleep, Orexin and Cognition Front Neurol Neurosci. 2021;45:38-51. 3: Kukkonen JP. Orexin/Hypocretin Signaling Curr Top Behav Neurosci. 2017;33:17-50. 4: Wu X, Xue T, Chen Z, Wang Z, Chen G. Orexin Receptor Antagonists and Insomnia Curr Psychiatry Rep. 2022 Oct;24(10):509-521. 5: Sun Y, Tisdale RK, Kilduff TS. Hypocretin/Orexin Receptor Pharmacology and Sleep Phases Front Neurol Neurosci. 2021;45:22-37. 6: Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y. Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment Nat Rev Neurol. 2019 Sep;15(9):519-539. 7: Nepovimova E, Janockova J, Misik J, Kubik S, Stuchlik A, Vales K, Korabecny J, Mezeiova E, Dolezal R, Soukup O, Kobrlova T, Pham NL, Nguyen TD, Konecny J, Kuca K. Orexin supplementation in narcolepsy treatment: A review Med Res Rev. 2019 May;39(3):961-975. 8: Han Y, Yuan K, Zheng Y, Lu L. Orexin Receptor Antagonists as Emerging Treatments for Psychiatric Disorders Neurosci Bull. 2020 Apr;36(4):432-448. 9: Pizza F, Barateau L, Dauvilliers Y, Plazzi G. The orexin story, sleep and sleep disturbances J Sleep Res. 2022 Aug;31(4):e13665. <a href="https://pubmed.ncbi.nlm.nih.gov/26600100">10: Schwartz MD, Kilduff TS. The Neurobiology of Sleep and Wakefulness Psychiatr Clin North Am. 2015 Dec;38(4):615-44. </a> <br><strong>Products Related to Orexin-B (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>