Guaiacol-d7
Product Specifications
UNSPSC Description
Guaiacol-d7 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].
Target Antigen
COX; Endogenous Metabolite; NF-κB
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OC1=C(C([2H])=C([2H])C([2H])=C1[2H])O
Molecular Weight
131.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27(2):801-7.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1065473-05-3
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