Methyllucidone
Methyllucidone is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and PI3K[1].
Product Specifications
CAS Number
[19956-54-8]
UNSPSC
12352005
Target
Keap1-Nrf2; PI3K; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/methyllucidone.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COC(/C=C/C1=CC=CC=C1)=C2C(C(OC)=CC\2=O)=O
Molecular Formula
C16H14O4
Molecular Weight
270.28
References & Citations
[1]Jee-Yun Park, et al. Methyl lucidone exhibits neuroprotective effects on glutamate-induced oxidative stress in HT-22 cells via Nrf-2/HO-1 signaling. Applied Biological Chemistry volume 62, Article number: 67 (2019) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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