Etamivan

Etamivan (Ethamivan; N, N-Diethylvanillamide) is an orally active respiratory stimulant. Ethamivan regulates breathing patterns by directly stimulating the medullary respiratory center, prioritizing increased breathing depth rather than frequency. Etamivan can be used in the research of barbiturate overdose and chronic obstructive pulmonary disease[1][2][3].

Product Specifications

CAS Number

[304-84-7]

Product Name Alternative

Ethamivan; N, N-Diethylvanillamide

UNSPSC

12352005

Hazard Statement

H301

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Etamivan.html

Concentration

10mM

Purity

99.63

Solubility

DMSO : ≥ 36 mg/mL

Smiles

O=C(N(CC)CC)C1=CC=C(O)C(OC)=C1

Molecular Formula

C12H17NO3

Molecular Weight

223.27

Precautions

H301

References & Citations

[1]WHEELDON PJ, et al. The use of ethamivan in the treatment of barbiturate poisoning. Can Med Assoc J. 1963;89 (1) :20-22.|[2]Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. J Pharmacol Exp Ther. 1975 May;193 (2) :657-63. |[3]Shimomura S, et al. Oral administration of the respiratory stimulant ethamivan in patients with pulmonary insufficiency. Am Rev Respir Dis. 1967;95 (4) :576-583.