(R)-Acalabrutinib
Product Specifications
UNSPSC Description
(R)-Acalabrutinib ((R)-ACP-196) is the enantiomer of Acalabrutinib (HY-17600). (R)-Acalabrutinib is an inhibitor for Bruton’s tyrosine kinase (BTK)[1].
Target Antigen
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-acalabrutinib.html
Solubility
10 mM in DMSO
Smiles
CC#CC(N1[C@H](CCC1)C2=NC(C3=CC=C(C=C3)C(NC4=CC=CC=N4)=O)=C5N2C=CN=C5N)=O
Molecular Weight
465.51
References & Citations
[1]Rayala VVSPK, et al., A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib. Chirality. 2022 Sep;34(9):1247-1256.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W062695/R-Acalabrutinib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W062695/
Clinical Information
No Development Reported
CAS Number
1952316-43-6
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