Topterone
Product Specifications
UNSPSC Description
Topterone is a topical antiandrogen.
Target Antigen
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Topterone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@](CCC)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O
Molecular Weight
330.50
References & Citations
[1]Ferrari RA, et al. Endocrine profile of topterone, a topical antiandrogen, in three species of laboratory animals. Methods Find Exp Clin Pharmacol. 1980 Apr;2(2):65-9.|[2]Chakrabarty K, et al. Mechanism of action of 17 alpha-propyltestosterone in inhibiting hamster flank organ development. J Invest Dermatol. 1980 Jan;74(1):5-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00198/Topterone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00198/
Clinical Information
No Development Reported
CAS Number
60607-35-4
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