Ganoderic acid H

Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling[1].

Product Specifications

CAS Number

[98665-19-1]

UNSPSC

12352211

Target

AP-1; NF-κB

Type

Natural Products

Related Pathways

Immunology/Inflammation; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ganoderic-acid-h.html

Purity

99.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(C1C2)C(O)CCC1(C)C3=C(C4(C(CC(C4(C(OC(C)=O)C3=O)C)C(C)CC(CC(C)C(O)=O)=O)=O)C)C2=O

Molecular Formula

C32H44O9

Molecular Weight

572.69

References & Citations

[1]Jiang J, et al. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. 2008 May;21 (5) :577-84.