1,4-Naphthoquinone-d6
Product Specifications
UNSPSC Description
1,4-Naphthoquinone-d6 is the deuterium labeled 1,4-Naphthoquinone[1]. 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[2].
Target Antigen
Monoamine Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C1C2=C([2H])C([2H])=C([2H])C([2H])=C2C(C([2H])=C1[2H])=O
Molecular Weight
164.19
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Coelho-Cerqueira E, et al. Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase. Chem Biol Drug Des. 2014 Apr;83(4):401-10.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
26473-08-5
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