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Antimycobacterial agent-10

Antimycobacterial agent-10 (compound 5) is a DNA gyrase inhibitor with anti-bacterial actiity (IC50=96 nM, M. tuberculosis gyrase) .

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimycobacterial-agent-10.html

Smiles

COC1=NC2=C(N=CC=C2C(O)CC3CCC(NCC4=CC(F)=C(Br)C(F)=C4)CC3)C=C1

Molecular Formula

C24H26BrF2N3O2

Molecular Weight

506.38

References & Citations

[1]Kokot M, et al. Structural Aspects of Mycobacterium tuberculosis DNA Gyrase Targeted by Novel Bacterial Topoisomerase Inhibitors[J]. ACS Medicinal Chemistry Letters, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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