Antimycobacterial agent-10
Antimycobacterial agent-10 (compound 5) is a DNA gyrase inhibitor with anti-bacterial actiity (IC50=96 nM, M. tuberculosis gyrase) .
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimycobacterial-agent-10.html
Smiles
COC1=NC2=C(N=CC=C2C(O)CC3CCC(NCC4=CC(F)=C(Br)C(F)=C4)CC3)C=C1
Molecular Formula
C24H26BrF2N3O2
Molecular Weight
506.38
References & Citations
[1]Kokot M, et al. Structural Aspects of Mycobacterium tuberculosis DNA Gyrase Targeted by Novel Bacterial Topoisomerase Inhibitors[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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