WFDC2 Recombinant Protein
Product Specifications
Background
Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.
CAS Number
9000-83-3
NCBI Gene ID
10406
Swiss Prot
Q14508
Accession Number
AAH46106
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Cancer
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
10.9 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
WAP four-disulfide core domain 2
NCBI Organism
Homo sapiens
Background Reference 01
Hellström, Ingegerd, et al., 2003, Cancer Research 63 (13) : 3695–3700.
Background Reference 02
Kirchhoff C., et al., 1992, Biol Reprod 45 (2) : 350–7.
Background Reference 03
Schummer M., et al., 1999, Gene 238 (2) : 375–85.
Other Product Names
HE4, WAP5, WFDC2, EDDM4
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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