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WFDC2 Recombinant Protein

Product Specifications

Background

Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.

CAS Number

9000-83-3

NCBI Gene ID

10406

Swiss Prot

Q14508

Accession Number

AAH46106

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Apoptosis, Cancer

Purity

>95% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

10.9 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

WAP four-disulfide core domain 2

NCBI Organism

Homo sapiens

Background Reference 01

Hellström, Ingegerd, et al., 2003, Cancer Research 63 (13) : 3695–3700.

Background Reference 02

Kirchhoff C., et al., 1992, Biol Reprod 45 (2) : 350–7.

Background Reference 03

Schummer M., et al., 1999, Gene 238 (2) : 375–85.

Other Product Names

HE4, WAP5, WFDC2, EDDM4

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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