BDNF Recombinant Protein
Product Specifications
Background
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75) . BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
NCBI Gene ID
627
Swiss Prot
P23560
Accession Number
P23560
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors, Neuroscience, Obesity, Signal Transduction, Stem Cell
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-062
Calculated Molecular Weight
27 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Brain-derived neurotrophic factor
NCBI Organism
Homo sapiens
Other Product Names
Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Species
Human
Protein ID
578877726
Physical Properties
Lyophilized
CAS Number
9000-83-3
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